| Immunogen | Syntheticpeptidefromthecarboxy-terminusoftheclonedratserotonintransporter. | 
| Host | GuineaPig | 
| Specificity | SerotoninTransporter.Theantiserumhasbeentestedontissuesectionsfromthecentralnervoussystem.ThestainingpatternobtainedwiththeAB1772correspondstothepatterndescribedusingantiserumtoserotoninitself.Theserotonintransporterimmunoreactivitycorrespondstowhathasbeendescribedusingotherantibodiestotheserotonintransporter.Preabsorptionoftheantiserumwiththeimmunogenpeptidecompletelyabolishestheimmunostaining. | 
| SpeciesReactivity |  | 
| AntibodyType | PolyclonalAntibody | 
| EntrezGeneNumber |  | 
| EntrezGeneSummary | Thisgeneencodesanintegralmembraneproteinthattransportstheneurotransmitterserotoninfromsynapticspacesintopresynapticneurons.Theencodedproteinterminatestheactionofserotoninandrecyclesitinasodium-dependentmanner.Thisproteinisatargetofpsychomotorstimulants,suchasamphetaminesandcocaine,andisamemberofthesodium:neurotransmittersymporterfamily.Arepeatlengthpolymorphisminthepromoterofthisgenehasbeenshowntoaffecttherateofserotoninuptakeandmayplayaroleinsuddeninfantdeathsyndrome,aggressivebehaviorinAlzheimerdiseasepatients,anddepression-susceptibilityinpeopleexperiencingemotionaltrauma. | 
| GeneSymbol | SLC6A45-HTT5HTTHTTOCD1hSERTSERT
 | 
| UniProtNumber |  | 
| UniProtSummary | FUNCTION:SwissProt:P31645#Terminatestheactionofserotoninbyitshighaffinitysodium-dependentreuptakeintopresynapticterminals. SIZE:630aminoacids;70325Da
 SUBUNIT:InteractswithTGFB1I1.
 SUBCELLULARLOCATION:Membrane;Multi-passmembraneprotein.
 SIMILARITY:SwissProt:P31645##Belongstothesodium:neurotransmittersymporter(SNF)family.
 MISCELLANEOUS:Thisproteinisthetargetofpsychomotorstimulantssuchasamphetaminesorcocaine.
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